management of 2, 4- dichlorophenoxyacetic acid intoxication by hemodialysis: a case report

نویسندگان

محمد مشیری

mohammad moshiri department of pharmacodynamic and toxicology, mashhad university of medical sciences, mashhad, iran. سید رضا موسوی

seyed reza mousavi department of clinical toxicology and medical toxicology, mashhad university of medical sciences, mashhad, iran. لیلا اعتماد

leila etemad phd.of toxicology, pharmaceutical research center, mashhad university of medical sciences, mashhad, iran.

چکیده

background: the herbicide 2, 4-dichlorophenoxyacetic acid (2, 4-d) can cause moderate to lethal poisoning. although urine alkalization has been recommended as the main treatment, hemodialysis (hd) may be more effective in severe cases. case: on 24th june 2014, a 53- year-old man ingested a high amount of 40% 2, 4-d. he suffered from mouth and epigastric burning sensation, vomiting and nausea. he was treated, in emam reza’s hospital of mashhad university of medical sciences, mashhad , iran,  with maintenance daily fluid infusion plus 10 meq/l nahco3. up to 9 hours after exposure, he became progressively stuporous. he developed diarrhea and hypotension, bp=100/60, unresponsive to volume replacement therapy. he received regular hemodialysis (hd) with bicarbonate for three hours. at the end of hd, his blood pressure rose to 110/70 and the level of consciousness began to improve. four hours later, he was fully conscious with stable blood pressure (130/80 mmhg). conclusion: hd may be an effective, safe and fast method for 2, 4-d high dose intoxication induced coma.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Management of 2, 4- Dichlorophenoxyacetic Acid Intoxication by Hemodialysis: A Case Report

Background: The herbicide 2, 4-dichlorophenoxyacetic acid (2, 4-D) can cause moderate to lethal poisoning. Although urine alkalization has been recommended as the main treatment, hemodialysis (HD) may be more effective in severe cases. Case: On 24th June 2014, a 53- year-old man ingested a high amount of 40% 2, 4-D. He suffered from mouth and epigastric burning sensation, vomiting and nausea...

متن کامل

2, 4-D Dichlorophenoxyacetic Acid Poisoning; Case Report and Literature Review

Background: 2, 4-dichlorophenoxyacetic acid, (2, 4-D) is a selective herbicide available as the acids, esters and several salts which vary in their chemical properties, environmental behaviour, and to a lesser extent toxicity. The salt and ester forms are derivatives of the parent acid. It is widely used as a weed killer. The 2, 4-D dimethylamine is one of the salts of this group. Case Presenta...

متن کامل

Microbial decomposition of 2, 4-dichlorophenoxyacetic acid.

ETCHELLS, J. L., COSTILOW, R. N., AND BELL, T. A. 1952 Identification of yeasts from commercial cucumber fermentations in northern brining areas. Farlowia, 4, 249-264. JANSEN, E. F., AND MACDONNELL, L. R. 1945 Influence of methoxyl content of pectic substances on the action of polygalacturonase. Arch. Biochem., 8, 97-112. JANSEN, E. F., MACDONNELL, L. R., AND JANG, R. 1945 Simultaneous actions ...

متن کامل

Peganum harmala intoxication, a case report

Objective: Peganum harmala (P. harmala), “Espand” in Persian, has small seeds and has been used in traditional medicine as emmenagogue and an abortifacient. It has various pharmacological effects such as antifungal, antibacterial, hypothermic, anticancer, antinociceptive, and reversible monoamine oxidase inhibition. Case details: This case was a 45 years old woman who ingested about 50 grams se...

متن کامل

photo -chemical degradation of 2, 4- dichlorophenoxyacetic acid (2, 4-d) in the effluent

background: 2, 4-dichlorophenoxy acetic acid (2, 4-d) is well known as inexpensive herbicides but it can give rise to undesirable pollution. the objective of this investigation was to describe a photo-chemical system for degradation of 2, 4-d. methods: a designed photolytic cell system was used in this study with a 150w or 400w uv lamp. a set of experiments was carried out at ph 1.5, 2.5, 3.5 a...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
iranian journal of toxicology

جلد ۱۰، شماره ۱، صفحات ۵۳-۵۵

کلمات کلیدی
[ 2 , 4 , ' d i c h l o r o p h e n o x y a c e t i c a c i d ' , ' a l k a l i n e d i u r e s i s ' , ' h e m o d i a l y s i s ' , ' h e r b i c i d e i n t o x i c a t i o n ' , ' i r a n . ' ]

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023